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      "name": "STATE STREET BANK AND TRUST COMPANY 505001 （常任代理人 株式会社みずほ銀行決済営業部）",
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    {
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      "shareholding_ratio": 11.48,
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      "rank": 3,
      "name": "STATE STREET BANK AND TRUST COMPANY 505001 （常任代理人 株式会社みずほ銀行決済営業部）",
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      "rank": 4,
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      "shareholding_ratio": 3.41,
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      "shareholding_ratio": 2.2,
      "shares_held": 6300000
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    {
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      "rank": 6,
      "name": "公益財団法人内藤記念科学振興財団",
      "shareholding_ratio": 1.47,
      "shares_held": 4212000
    },
    {
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      "period": "2022/3",
      "rank": 7,
      "name": "STATE STREET BANK WEST CLIENT-TREATY 505234 （常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 1.38,
      "shares_held": 3965000
    },
    {
      "FY": "FY21",
      "period": "2022/3",
      "rank": 8,
      "name": "JPモルガン証券株式会社",
      "shareholding_ratio": 1.28,
      "shares_held": 3663000
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    {
      "FY": "FY21",
      "period": "2022/3",
      "rank": 9,
      "name": "GOVERNMENT OF NORWAY （常任代理人シティバンク、エヌ・エイ東京支店）",
      "shareholding_ratio": 1.2,
      "shares_held": 3429000
    },
    {
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      "period": "2022/3",
      "rank": 10,
      "name": "JP MORGAN CHASE BANK 385781 （常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 1.2,
      "shares_held": 3429000
    },
    {
      "FY": "FY22",
      "period": "2023/3",
      "rank": 1,
      "name": "日本マスタートラスト信託銀行株式会社（信託口）",
      "shareholding_ratio": 19.31,
      "shares_held": 55397000
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    {
      "FY": "FY22",
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      "rank": 2,
      "name": "株式会社日本カストディ銀行 （信託口）",
      "shareholding_ratio": 12.61,
      "shares_held": 36175000
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    {
      "FY": "FY22",
      "period": "2023/3",
      "rank": 3,
      "name": "STATE STREET BANK AND TRUST COMPANY 505001 （常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 7.15,
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    {
      "FY": "FY22",
      "period": "2023/3",
      "rank": 4,
      "name": "日本生命保険相互会社 （常任代理人 日本マスタートラスト信託銀行株式会社）",
      "shareholding_ratio": 3,
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    {
      "FY": "FY22",
      "period": "2023/3",
      "rank": 5,
      "name": "株式会社埼玉りそな銀行",
      "shareholding_ratio": 1.85,
      "shares_held": 5300000
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    {
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      "period": "2023/3",
      "rank": 6,
      "name": "STATE STREET BANK WEST CLIENT-TREATY 505234 （常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 1.61,
      "shares_held": 4606000
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    {
      "FY": "FY22",
      "period": "2023/3",
      "rank": 7,
      "name": "GOLDMAN,SACHS & CO.REG （常任代理人 ゴールドマン・サックス証券株式会社）",
      "shareholding_ratio": 1.49,
      "shares_held": 4269000
    },
    {
      "FY": "FY22",
      "period": "2023/3",
      "rank": 8,
      "name": "公益財団法人内藤記念科学振興財団",
      "shareholding_ratio": 1.47,
      "shares_held": 4212000
    },
    {
      "FY": "FY22",
      "period": "2023/3",
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      "company_name_at_period": "エーザイ",
      "rank": 8,
      "name": "安田信託銀行",
      "shareholding_ratio": 1.9,
      "shares_held": 1307000,
      "total_shares": 68897000,
      "source": "企業系列総覧 1981年版"
    },
    {
      "FY": "FY80",
      "period": "1980/4",
      "company_name_at_period": "エーザイ",
      "rank": 9,
      "name": "日本証券金融",
      "shareholding_ratio": 1.84,
      "shares_held": 1268000,
      "total_shares": 68897000,
      "source": "企業系列総覧 1981年版"
    },
    {
      "FY": "FY80",
      "period": "1980/4",
      "company_name_at_period": "エーザイ",
      "rank": 10,
      "name": "内藤祐次",
      "shareholding_ratio": 1.78,
      "shares_held": 1223000,
      "total_shares": 68897000,
      "source": "企業系列総覧 1981年版"
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      "company_name_at_period": "エーザイ",
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      "name": "日本マスタートラスト信託銀行",
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      "total_shares": null,
      "source": "有価証券報告書（2006年3月期）"
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    {
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      "company_name_at_period": "エーザイ",
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      "shares_held": 14005000,
      "total_shares": null,
      "source": "有価証券報告書（2006年3月期）"
    },
    {
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      "company_name_at_period": "エーザイ",
      "rank": 3,
      "name": "日本生命保険",
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      "shares_held": 13827000,
      "total_shares": null,
      "source": "有価証券報告書（2006年3月期）"
    },
    {
      "FY": "FY05",
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      "company_name_at_period": "エーザイ",
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      "name": "埼玉りそな銀行",
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      "shares_held": 12398000,
      "total_shares": null,
      "source": "有価証券報告書（2006年3月期）"
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    {
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      "company_name_at_period": "エーザイ",
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      "name": "ザ チェース マンハッタン バンク エヌエイ ロンドン エスエル オムニバス アカウント",
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      "source": "有価証券報告書（2006年3月期）"
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      "source": "有価証券報告書（2006年3月期）"
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      "name": "みずほコーポレート銀行",
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      "source": "有価証券報告書（2006年3月期）"
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    {
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      "shares_held": 6437000,
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      "source": "有価証券報告書（2006年3月期）"
    },
    {
      "FY": "FY05",
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      "company_name_at_period": "エーザイ",
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      "source": "有価証券報告書（2006年3月期）"
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      "source": "有価証券報告書（2006年3月期）"
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      "source": "有価証券報告書（2010年3月期）"
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    {
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      "source": "有価証券報告書（2010年3月期）"
    },
    {
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      "source": "有価証券報告書（2010年3月期）"
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    {
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      "name": "埼玉りそな銀行",
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      "source": "有価証券報告書（2010年3月期）"
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    {
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      "company_name_at_period": "エーザイ",
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      "source": "有価証券報告書（2010年3月期）"
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    {
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      "source": "有価証券報告書（2010年3月期）"
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    {
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      "source": "有価証券報告書（2010年3月期）"
    },
    {
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      "name": "みずほコーポレート銀行",
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      "source": "有価証券報告書（2010年3月期）"
    },
    {
      "FY": "FY09",
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      "source": "有価証券報告書（2010年3月期）"
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    {
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      "rank": 1,
      "name": "日本トラスティ・サービス信託銀行(信託口)",
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      "shares_held": 20801000,
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      "source": "有価証券報告書（2015年3月期）"
    },
    {
      "FY": "FY14",
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      "name": "日本マスタートラスト信託銀行(信託口)",
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      "source": "有価証券報告書（2015年3月期）"
    },
    {
      "FY": "FY14",
      "period": "2015/3",
      "company_name_at_period": "エーザイ",
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      "name": "日本生命保険",
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      "total_shares": null,
      "source": "有価証券報告書（2015年3月期）"
    },
    {
      "FY": "FY14",
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      "company_name_at_period": "エーザイ",
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      "name": "JP MORGAN CHASE BANK 385147",
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      "shares_held": 8937000,
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      "source": "有価証券報告書（2015年3月期）"
    },
    {
      "FY": "FY14",
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      "name": "埼玉りそな銀行",
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      "total_shares": null,
      "source": "有価証券報告書（2015年3月期）"
    },
    {
      "FY": "FY14",
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      "source": "有価証券報告書（2015年3月期）"
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    {
      "FY": "FY14",
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      "name": "エーザイ従業員持株会",
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      "total_shares": null,
      "source": "有価証券報告書（2015年3月期）"
    },
    {
      "FY": "FY14",
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      "source": "有価証券報告書（2015年3月期）"
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    {
      "FY": "FY14",
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      "company_name_at_period": "エーザイ",
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      "source": "有価証券報告書（2015年3月期）"
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    {
      "FY": "FY14",
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      "source": "有価証券報告書（2015年3月期）"
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  ]
}
