{
  "commentary": [
    {
      "heading": null,
      "paragraphs": [
        "2002年のロシュ傘下化を起点に、Roche Holding Ltdが筆頭株主として60%超を一貫保有しており、FY15の59.89%からFY25でも61.10%と支配構造は固定化している。",
        "浮動株側では日本マスタートラスト信託銀行がFY15の3.54%からFY22に9.03%まで集中化し、ロシュ支配下での機関化が進展している。"
      ]
    }
  ],
  "shareholders": [
    {
      "FY": "FY15",
      "period": "2015/12",
      "rank": 1,
      "name": "ロシュ・ホールディング・リミテッド（常任代理人 西村あさひ法律事務所）",
      "shareholding_ratio": 59.89,
      "shares_held": 335223000
    },
    {
      "FY": "FY15",
      "period": "2015/12",
      "rank": 2,
      "name": "日本マスタートラスト信託銀行株式会社（信託口）",
      "shareholding_ratio": 3.54,
      "shares_held": 19857000
    },
    {
      "FY": "FY15",
      "period": "2015/12",
      "rank": 3,
      "name": "日本トラスティ・サービス信託銀行株式会社（信託口）",
      "shareholding_ratio": 3.08,
      "shares_held": 17244000
    },
    {
      "FY": "FY15",
      "period": "2015/12",
      "rank": 4,
      "name": "ジェー ピー モルガン チェース バンク ３８５１４７ （常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 1.51,
      "shares_held": 8495000
    },
    {
      "FY": "FY15",
      "period": "2015/12",
      "rank": 5,
      "name": "ジェー ピー モルガン チェース バンク ３８００５５ （常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 1.13,
      "shares_held": 6374000
    },
    {
      "FY": "FY15",
      "period": "2015/12",
      "rank": 6,
      "name": "ゴールドマン・サックス・アンド・カンパニーレギュラーアカウント（常任代理人 ゴールドマン・サックス証券株式会社）",
      "shareholding_ratio": 0.65,
      "shares_held": 3660000
    },
    {
      "FY": "FY15",
      "period": "2015/12",
      "rank": 7,
      "name": "ステート ストリート バンク ウェスト クライアント トリーティー ５０５２３４ （常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 0.65,
      "shares_held": 3644000
    },
    {
      "FY": "FY15",
      "period": "2015/12",
      "rank": 8,
      "name": "資産管理サービス信託銀行株式会社（投信受入担保口）",
      "shareholding_ratio": 0.64,
      "shares_held": 3594000
    },
    {
      "FY": "FY15",
      "period": "2015/12",
      "rank": 9,
      "name": "東京海上日動火災保険株式会社",
      "shareholding_ratio": 0.58,
      "shares_held": 3282000
    },
    {
      "FY": "FY15",
      "period": "2015/12",
      "rank": 10,
      "name": "ザ バンク オブ ニューヨーク メロン ＳＡ／ＮＶ １０ （常任代理人 株式会社三菱東京ＵＦＪ銀行）",
      "shareholding_ratio": 0.57,
      "shares_held": 3232000
    },
    {
      "FY": "FY16",
      "period": "2016/12",
      "rank": 1,
      "name": "ROCHE HOLDING LTD （常任代理人 西村あさひ法律事務所）",
      "shareholding_ratio": 59.89,
      "shares_held": 335223000
    },
    {
      "FY": "FY16",
      "period": "2016/12",
      "rank": 2,
      "name": "日本マスタートラスト信託銀行株式会社（信託口）",
      "shareholding_ratio": 3.97,
      "shares_held": 22271000
    },
    {
      "FY": "FY16",
      "period": "2016/12",
      "rank": 3,
      "name": "日本トラスティ・サービス信託銀行株式会社（信託口）",
      "shareholding_ratio": 3.31,
      "shares_held": 18540000
    },
    {
      "FY": "FY16",
      "period": "2016/12",
      "rank": 4,
      "name": "JP MORGAN CHASE BANK 385147 （常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 2.55,
      "shares_held": 14288000
    },
    {
      "FY": "FY16",
      "period": "2016/12",
      "rank": 5,
      "name": "JP MORGAN CHASE BANK 380055 （常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 0.87,
      "shares_held": 4920000
    },
    {
      "FY": "FY16",
      "period": "2016/12",
      "rank": 6,
      "name": "JP MORGAN CHASE BANK 385632 （常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 0.79,
      "shares_held": 4476000
    },
    {
      "FY": "FY16",
      "period": "2016/12",
      "rank": 7,
      "name": "資産管理サービス信託銀行株式会社（証券投資信託口）",
      "shareholding_ratio": 0.72,
      "shares_held": 4045000
    },
    {
      "FY": "FY16",
      "period": "2016/12",
      "rank": 8,
      "name": "STATE STREET BANK WEST CLIENT - TREATY 505234 （常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 0.67,
      "shares_held": 3761000
    },
    {
      "FY": "FY16",
      "period": "2016/12",
      "rank": 9,
      "name": "中外製薬社員持株会",
      "shareholding_ratio": 0.56,
      "shares_held": 3158000
    },
    {
      "FY": "FY16",
      "period": "2016/12",
      "rank": 10,
      "name": "住友生命保険相互会社 （常任代理人 日本トラスティ・サービス信託銀行株式会社）",
      "shareholding_ratio": 0.53,
      "shares_held": 3000000
    },
    {
      "FY": "FY17",
      "period": "2017/12",
      "rank": 1,
      "name": "ROCHE HOLDING LTD（常任代理人 西村あさひ法律事務所）",
      "shareholding_ratio": 59.89,
      "shares_held": 335223000
    },
    {
      "FY": "FY17",
      "period": "2017/12",
      "rank": 2,
      "name": "日本マスタートラスト信託銀行株式会社（信託口）",
      "shareholding_ratio": 4.49,
      "shares_held": 25154000
    },
    {
      "FY": "FY17",
      "period": "2017/12",
      "rank": 3,
      "name": "日本トラスティ・サービス信託銀行株式会社（信託口）",
      "shareholding_ratio": 2.92,
      "shares_held": 16386000
    },
    {
      "FY": "FY17",
      "period": "2017/12",
      "rank": 4,
      "name": "JP MORGAN CHASE BANK 385147（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 2.87,
      "shares_held": 16087000
    },
    {
      "FY": "FY17",
      "period": "2017/12",
      "rank": 5,
      "name": "JP MORGAN CHASE BANK 380055（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 1.63,
      "shares_held": 9151000
    },
    {
      "FY": "FY17",
      "period": "2017/12",
      "rank": 6,
      "name": "STATE STREET BANK WEST CLIENT-TREATY 505234（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 0.76,
      "shares_held": 4262000
    },
    {
      "FY": "FY17",
      "period": "2017/12",
      "rank": 7,
      "name": "日本トラスティ・サービス信託銀行株式会社（信託口５）",
      "shareholding_ratio": 0.71,
      "shares_held": 3975000
    },
    {
      "FY": "FY17",
      "period": "2017/12",
      "rank": 8,
      "name": "日本トラスティ・サービス信託銀行株式会社（信託口７）",
      "shareholding_ratio": 0.67,
      "shares_held": 3794000
    },
    {
      "FY": "FY17",
      "period": "2017/12",
      "rank": 9,
      "name": "JP MORGAN CHASE BANK 385632（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 0.67,
      "shares_held": 3792000
    },
    {
      "FY": "FY17",
      "period": "2017/12",
      "rank": 10,
      "name": "MSCO CUSTOMER SECURITIES（常任代理人 モルガン・スタンレーMUFG証券株式会社）",
      "shareholding_ratio": 0.57,
      "shares_held": 3219000
    },
    {
      "FY": "FY18",
      "period": "2018/12",
      "rank": 1,
      "name": "ROCHE HOLDING LTD（常任代理人 西村あさひ法律事務所）",
      "shareholding_ratio": 61.25,
      "shares_held": 335223000
    },
    {
      "FY": "FY18",
      "period": "2018/12",
      "rank": 2,
      "name": "日本マスタートラスト信託銀行株式会社（信託口）",
      "shareholding_ratio": 5.36,
      "shares_held": 29342000
    },
    {
      "FY": "FY18",
      "period": "2018/12",
      "rank": 3,
      "name": "日本トラスティ・サービス信託銀行株式会社（信託口）",
      "shareholding_ratio": 2.98,
      "shares_held": 16320000
    },
    {
      "FY": "FY18",
      "period": "2018/12",
      "rank": 4,
      "name": "STATE STREET BANK AND TRUST COMPANY 505001（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 2.85,
      "shares_held": 15614000
    },
    {
      "FY": "FY18",
      "period": "2018/12",
      "rank": 5,
      "name": "JP MORGAN CHASE BANK 380055（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 2.54,
      "shares_held": 13924000
    },
    {
      "FY": "FY18",
      "period": "2018/12",
      "rank": 6,
      "name": "STATE STREET BANK WEST CLIENT-TREATY 505234（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 0.77,
      "shares_held": 4231000
    },
    {
      "FY": "FY18",
      "period": "2018/12",
      "rank": 7,
      "name": "日本トラスティ・サービス信託銀行株式会社（信託口５）",
      "shareholding_ratio": 0.74,
      "shares_held": 4091000
    },
    {
      "FY": "FY18",
      "period": "2018/12",
      "rank": 8,
      "name": "資産管理サービス信託銀行株式会社（証券投資信託口）",
      "shareholding_ratio": 0.69,
      "shares_held": 3829000
    },
    {
      "FY": "FY18",
      "period": "2018/12",
      "rank": 9,
      "name": "日本トラスティ・サービス信託銀行株式会社（信託口７）",
      "shareholding_ratio": 0.68,
      "shares_held": 3748000
    },
    {
      "FY": "FY18",
      "period": "2018/12",
      "rank": 10,
      "name": "SSBTC CLIENT OMNIBUS ACCOUNT（常任代理人 香港上海銀行東京支店 カストディ業務部）",
      "shareholding_ratio": 0.66,
      "shares_held": 3651000
    },
    {
      "FY": "FY19",
      "period": "2019/12",
      "rank": 1,
      "name": "ROCHE HOLDING LTD（常任代理人 西村あさひ法律事務所）",
      "shareholding_ratio": 61.22,
      "shares_held": 335223000
    },
    {
      "FY": "FY19",
      "period": "2019/12",
      "rank": 2,
      "name": "日本マスタートラスト信託銀行株式会社（信託口）",
      "shareholding_ratio": 5.52,
      "shares_held": 30258000
    },
    {
      "FY": "FY19",
      "period": "2019/12",
      "rank": 3,
      "name": "JP MORGAN CHASE BANK380055（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 2.99,
      "shares_held": 16388000
    },
    {
      "FY": "FY19",
      "period": "2019/12",
      "rank": 4,
      "name": "日本トラスティ・サービス信託銀行株式会社（信託口）",
      "shareholding_ratio": 2.93,
      "shares_held": 16075000
    },
    {
      "FY": "FY19",
      "period": "2019/12",
      "rank": 5,
      "name": "STATE STREET BANK AND TRUST COMPANY 505001（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 1.92,
      "shares_held": 10537000
    },
    {
      "FY": "FY19",
      "period": "2019/12",
      "rank": 6,
      "name": "日本トラスティ・サービス信託銀行株式会社（信託口７）",
      "shareholding_ratio": 0.86,
      "shares_held": 4756000
    },
    {
      "FY": "FY19",
      "period": "2019/12",
      "rank": 7,
      "name": "日本トラスティ・サービス信託銀行株式会社（信託口５）",
      "shareholding_ratio": 0.77,
      "shares_held": 4230000
    },
    {
      "FY": "FY19",
      "period": "2019/12",
      "rank": 8,
      "name": "STATE STREET BANK WEST CLIENT-TREATY 505234（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 0.73,
      "shares_held": 3998000
    },
    {
      "FY": "FY19",
      "period": "2019/12",
      "rank": 9,
      "name": "SSBTC CLIENT OMNIBUS ACCOUNT（常任代理人 香港上海銀行東京支店 カストディ業務部）",
      "shareholding_ratio": 0.69,
      "shares_held": 3795000
    },
    {
      "FY": "FY19",
      "period": "2019/12",
      "rank": 10,
      "name": "NORTHERN TRUST CO.（AVFC）SUB A/C AMERICAN CLIENTS（常任代理人 香港上海銀行東京支店 カストディ業務部）",
      "shareholding_ratio": 0.64,
      "shares_held": 3528000
    },
    {
      "FY": "FY20",
      "period": "2020/12",
      "rank": 1,
      "name": "ROCHE HOLDING LTD（常任代理人 西村あさひ法律事務所）",
      "shareholding_ratio": 61.17,
      "shares_held": 1005670000
    },
    {
      "FY": "FY20",
      "period": "2020/12",
      "rank": 2,
      "name": "日本マスタートラスト信託銀行株式会社（信託口）",
      "shareholding_ratio": 6.44,
      "shares_held": 105907000
    },
    {
      "FY": "FY20",
      "period": "2020/12",
      "rank": 3,
      "name": "JP MORGAN CHASE BANK385632（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 3.68,
      "shares_held": 60658000
    },
    {
      "FY": "FY20",
      "period": "2020/12",
      "rank": 4,
      "name": "株式会社日本カストディ銀行（信託口）",
      "shareholding_ratio": 2.95,
      "shares_held": 48548000
    },
    {
      "FY": "FY20",
      "period": "2020/12",
      "rank": 5,
      "name": "株式会社日本カストディ銀行（信託口７）",
      "shareholding_ratio": 1.12,
      "shares_held": 18546000
    },
    {
      "FY": "FY20",
      "period": "2020/12",
      "rank": 6,
      "name": "SSBTC CLIENT OMNIBUSACCOUNT（常任代理人 香港上海銀行東京支店 カストディ業務部）",
      "shareholding_ratio": 0.88,
      "shares_held": 14518000
    },
    {
      "FY": "FY20",
      "period": "2020/12",
      "rank": 7,
      "name": "STATE STREET BANK WESTCLIENT-TREATY 505234（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 0.87,
      "shares_held": 14460000
    },
    {
      "FY": "FY20",
      "period": "2020/12",
      "rank": 8,
      "name": "STATE STREET BANK ANDTRUST COMPANY 505001（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 0.74,
      "shares_held": 12283000
    },
    {
      "FY": "FY20",
      "period": "2020/12",
      "rank": 9,
      "name": "株式会社日本カストディ銀行（信託口５）",
      "shareholding_ratio": 0.6,
      "shares_held": 9930000
    },
    {
      "FY": "FY20",
      "period": "2020/12",
      "rank": 10,
      "name": "株式会社日本カストディ銀行（証券投資信託口）",
      "shareholding_ratio": 0.59,
      "shares_held": 9849000
    },
    {
      "FY": "FY21",
      "period": "2021/12",
      "rank": 1,
      "name": "ROCHE HOLDING LTD（常任代理人 西村あさひ法律事務所）",
      "shareholding_ratio": 61.16,
      "shares_held": 1005670000
    },
    {
      "FY": "FY21",
      "period": "2021/12",
      "rank": 2,
      "name": "日本マスタートラスト信託銀行株式会社（信託口）",
      "shareholding_ratio": 8.76,
      "shares_held": 144080000
    },
    {
      "FY": "FY21",
      "period": "2021/12",
      "rank": 3,
      "name": "株式会社日本カストディ銀行（信託口）",
      "shareholding_ratio": 2.99,
      "shares_held": 49225000
    },
    {
      "FY": "FY21",
      "period": "2021/12",
      "rank": 4,
      "name": "SMBC日興証券株式会社",
      "shareholding_ratio": 1.09,
      "shares_held": 18063000
    },
    {
      "FY": "FY21",
      "period": "2021/12",
      "rank": 5,
      "name": "STATE STREET BANK WESTCLIENT-TREATY 505234（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 0.83,
      "shares_held": 13782000
    },
    {
      "FY": "FY21",
      "period": "2021/12",
      "rank": 6,
      "name": "JP MORGAN CHASE BANK385632（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 0.83,
      "shares_held": 13706000
    },
    {
      "FY": "FY21",
      "period": "2021/12",
      "rank": 7,
      "name": "STATE STREET BANK ANDTRUST COMPANY 505001（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 0.77,
      "shares_held": 12815000
    },
    {
      "FY": "FY21",
      "period": "2021/12",
      "rank": 8,
      "name": "株式会社日本カストディ銀行（証券投資信託口）",
      "shareholding_ratio": 0.62,
      "shares_held": 10253000
    },
    {
      "FY": "FY21",
      "period": "2021/12",
      "rank": 9,
      "name": "住友生命保険相互会社（常任代理人 株式会社日本カストディ銀行）",
      "shareholding_ratio": 0.54,
      "shares_held": 9000000
    },
    {
      "FY": "FY21",
      "period": "2021/12",
      "rank": 10,
      "name": "NORTHERN TRUST CO.（AVFC）SUB A/C AMERICAN CLIENTS（常任代理人 香港上海銀行東京支店 カストディ業務部）",
      "shareholding_ratio": 0.53,
      "shares_held": 8871000
    },
    {
      "FY": "FY22",
      "period": "2022/12",
      "rank": 1,
      "name": "ROCHE HOLDING LTD（常任代理人 西村あさひ法律事務所）",
      "shareholding_ratio": 61.13,
      "shares_held": 1005670000
    },
    {
      "FY": "FY22",
      "period": "2022/12",
      "rank": 2,
      "name": "日本マスタートラスト信託銀行株式会社（信託口）",
      "shareholding_ratio": 9.03,
      "shares_held": 148700000
    },
    {
      "FY": "FY22",
      "period": "2022/12",
      "rank": 3,
      "name": "株式会社日本カストディ銀行（信託口）",
      "shareholding_ratio": 3.73,
      "shares_held": 61476000
    },
    {
      "FY": "FY22",
      "period": "2022/12",
      "rank": 4,
      "name": "SMBC日興証券株式会社",
      "shareholding_ratio": 1.18,
      "shares_held": 19524000
    },
    {
      "FY": "FY22",
      "period": "2022/12",
      "rank": 5,
      "name": "JPモルガン証券株式会社",
      "shareholding_ratio": 0.93,
      "shares_held": 15441000
    },
    {
      "FY": "FY22",
      "period": "2022/12",
      "rank": 6,
      "name": "STATE STREET BANK WESTCLIENT-TREATY 505234（常任代理人 株式会社みずほ銀行決済営業部）",
      "shareholding_ratio": 0.87,
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      "source": "株式会社年鑑 昭和31年版"
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      "source": "株式会社年鑑 昭和37年版"
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      "total_shares": 36000000,
      "source": "株式会社年鑑 昭和37年版"
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    {
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      "company_name_at_period": "中外製薬",
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    {
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}
